Vascular Disease Management
INSIGHT INTO DIAGNOSIS AND TREATMENT OF VASCULAR DISEASE
MANAGEMENT
Thursday, May 15, 2008

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Featured Article

330
Vascular Disease Management - ISSN: 1553-8036 - Volume 1 - Issue 1 - October 2004
Vance Sohn, MD, Zachary Arthurs, MD, Charles Andersen, MD
Ulnar artery aneurysms are uncommon and have been linked with traumatic injuries to the hand. These aneurysms are most commonly seen in workers who use the hypothenar eminence of their hands as a hammer and can be accompanied by a constellation of symptoms. Both penetrating and blunt trauma have been documented as sources of ulnar artery aneurysms and its subsequent sequela. In this case report, we describe a 45-year-old gentleman who presented with digital ischemia of his 4th and 5th digits and other clinical symptoms of the hypothenar hammer syndrome after performing manual labor. His initial management, method of diagnosis, operative intervention, and peri-operative management are discussed. Ulnar artery aneurysms, while uncommon, can lead to a limb-threatening event. A high index of suspicion for ulnar artery aneurysms must be considered in patients with an antecedent history of acute or repetitive trauma. While there are multiple diagnostic modalities and minimally invasive altern
Nicolas W. Shammas, MD, MS
Embolization following percutaneous intervention is a universal problem occurring in all vascular beds, including the periphery. Embolic filter protection (EFP) is effective in capturing macrodebris following percutaneous peripheral interventions (PPI). Predictors of distal lower extremity embolization appear to be a recent onset of symptoms in patients with total or subtotal occlusion, long, irregular and calcified lesions, degenerative grafts, intraluminal filling defects, and the use of the Silverhawk atherectomy device and mechanical thrombectomy. Filters have their own set of potential problems, and filter retrieval is probably one of the key steps where problems are likely to occur. In this manuscript, we discuss embolization in the lower extremity following PPI, and provide tips on how to avoid problems with embolic filter protection use.
1Ruth L. Bush, MD and 2Peter H. Lin, MD
The following special CME section is underwritten through an educational grant from Possis Medical, Inc.
VDM editorial board members share their thoughts
Frank J. Criado, Editor-in-Chief
A unique journal designed with the multi-disciplinary nature of today's vascular team in mind
Corey Goldman, MD, PhD

Excimer Laser-Assisted Angioplasty in Severe Infrapopliteal Disease and CLI: The CIS "LACI Equivalent" Experience
David E. Allie
Background: 12-month major amputation rates in “true limb salvage” (Rutherford class 5-6 with established tissue loss) are reported as > 90% if nonrevascularable and 25% if revascularable. Twenty-four month mortality rates of > 40-50% are reported post amputation and < 50% will ambulate with a prosthesis. The encouraging Laser Angioplasty for Critical Limb Ischemia (LACI) 6-month limb salvage (LS) rate of 93% prompted adoption of excimer laser assisted angioplasty as one of our primary infrapopliteal treatments for “TLS.” Methods: Between October 2001 – October 2003, 62 patients (62 limbs) with Rutherford class 5-6 symptoms presented with severe infrapopliteal disease without single vessel “straight line flow” to the foot. Seventy infrapopliteal arteries (IA) were treated, including posterior tibial 21/70 (30%), peroneal 16/70 (23%), anterior tibial 8/70 (11%), tibioperoneal trunk 14/70 (20%), and multiple 11/70 (16%). Thirty out of 62 (48%) and 22/62 (35%) required supe

Intracranial Middle Cerebral Artery Percutaneous Intervention Using a Drug-Eluting Stent
Jacqueline Saw, MD, Jay S. Yadav, MD, Cameron Haery, MD, Derk W. Krieger, MD, Alex Abou-Chebl, MD
The use of bare-metal stents for intracranial vessels is associated with relatively high restenosis rates. We report the first human use of a sirolimus-eluting stent for a symptomatic proximal middle cerebral artery stenosis. This stent was successfully delivered and deployed without complications, with excellent one month angiographic results.

Bivalirudin in Peripheral Vascular Interventions: A Single Center Experience
Nicolas W. Shammas, MS, MD, *Jon H. Lemke, PhD, Eric J. Dippel, MD, *Dawn E. McKinney, MA, Vickie S. Takes, RN, Monica Youngblut, RN, Melodee Harris, RN
Unfractionated heparin is a widely utilized anticoagulant during peripheral angioplasty procedures (PTA). In contrast to heparin, bivalirudin is a direct thrombin inhibitor with predictable anticoagulation, does not activate platelets, and inhibits both soluble and bound thrombin. The experience with bivalirudin during PTA remains limited. In this single-center prospective study, 48 consecutive patients (60.4% males, mean age 70.0 ± 12.1) received bivalirudin as the primary anticoagulant during PTA (0.75 mg/kg bolus, 1.75 mg/kg/h during the procedure). Thirty-four (70.8%) had claudication and 6 (12.5%) had ulceration. Thrombus was angiographically seen in 3 (6.3%) patients. In-hospital serious procedural complications were limited to 2 (4.2%) (exact 95% confidence interval: (0.5%,14.3%]) patients with major bleeding; none (0.0%) of the other following endpoints occurred: death, limb loss, emergent need for revascularization of the same vessel, embolic strokes, and vascular complication

Update: Bivalirudin in Peripheral Vascular Intervention
Nicolas W. Shammas, MS, MD
An interview with Phillip Purdy, MD

VASCULAR TOPICS

Peripheral Angioplasty
Thoracic Stent Grafts
Renal Stenting
Vena Cava Filter
Hemodialysis Management
Computed Tomography
PFO Closure
SFA Stenting
Carotid Stenting
Vessel Closure
Angiography
Carotid Endarterectomy
Ultrasound

Critical Limb Ischemia
Superficial Femoral Artery
Embolization
Device Based Thrombectomy
Pharmacological Management
MRA
Mesenteric Artery Stenting
AAA Stent Grafts
Iliac Stenting
Thrombolysis Procedures Using Drug Therapy

SUPPLEMENTS

Superior Mesenteric Artery Revascularization and Retrograde Visualization
This clinical case update was supported through an unrestricted educational grant from Terumo Medical Corporation.

HMP Increased Cutaneous Sensibility in Patients with Diabetic Neuropathy Utilizing a Pharmacological Approach — Clinical Case Evidence

This clinical case update was supported through an unrestricted educational grant from Pamlab, LLC.

A New Biological Approachto Below-Knee Revascularization
A Review of the GORE PROPATEN Vascular Graft:
The Combination That Lasts

This special supplement was made possible through a grant from W. L. Gore

Combining Bilayered Living Cell Therapy with Minimally Invasive Vein Surgery:
Current Treatment Strategies for Venous Ulcers

This activity is supported by an educational grant from Organogenesis.

Pharmacotherapy in Peripheral Vascular Disease

Platelet Inhibition in Critical Limb Ischemia and Peripheral Vascular Interventions
DAVID E. ALLIE, MD

An Overview of Pharmacotherapy during Percutaneous Peripheral Interventions of Thrombotic Lesions
NICOLAS W. SHAMMAS, MD, MS, FACC


The Important Properties of Contrast Media: Focus on Viscosity

This special supplement was made possible through a grant from Guerbet LLC

RECENTLY ADDED

Anticoagulation Techniques for Peripheral Vascular Interventions

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